Even if BA.2.86 does becomes widespread — and proves adept at dodging neutralizing antibodies, which seems likely, on the basis of its set of spike mutations — other forms of immunity will probably stop most people from getting seriously ill if they are infected, Bloom adds.
Ok, still something to keep an eye out, but it might not be that devastating as it once was back in 2019-2020
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T cells.
“Most studies on COVID-19 vaccines have focused on neutralizing antibody (NAb) responses, with little emphasis on cellular immunity. However, accumulating data suggest that T cell responses play an important role in vaccine protection against severe COVID-19 disease, particularly against viral variants that partially escape from recognition by NAbs. These insights have implications for using current COVID-19 vaccines and for developing next-generation vaccines against COVID-19 and other infectious diseases”
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Yeah, the Pirola variant has around 30 mutations as compared to other variants recently. The actual effect of these mutations is still being investigated, but what has been uncovered thus far doesn’t look good.
