• InverseParallax@lemmy.world
    link
    fedilink
    English
    arrow-up
    2
    ·
    9 hours ago

    First pass metabolism, or just absorbed by mucous membranes of the mouth, blood flow isn’t great so absorption is less systemic, just mess up your mouth and throat a bit really, but might help some symptoms locally.

    The nasal dose is low compared to oral and those dissolve in areas with high blood uptake.